Level-graded English lessons with reading, listening, activities, and discussion.
Lesson Info
Lesson Content
Warm-up, Vocab List, Reading and Audio
Understanding: True or False, Put Events in Order, Multiple Choice
Language: Vocab Match
Use It: Discussion Builder, Discussion Questions
Answers
Think Ahead: What do you think scientists need to learn next?
a) Whether mice can remember human faces.
b) Whether the drug may also help people.
c) Whether Alzheimer's can be spread between animals.

Ask: (1) Do you have a good memory? (2) Have you ever heard of Alzheimer's disease?
Vocab List
Reading
Scientists say they brought back brain function in mice with Alzheimer's disease. Alzheimer's is a brain disease. It slowly takes away a person's memory and thinking. It mostly affects people over 65. It is the main cause of dementia (when the brain stops working well). More than 150 million people could have dementia by 2050.
The scientists tested a new drug on sick mice. The drug helped the mice's brains get energy again. Even very sick mice got better after the treatment. Their brains started working normally again.
The scientists tested the drug on two different groups of mice. In both groups, the drug stopped the disease or brought back brain function. The scientists now think that even very bad Alzheimer's can get better.
But the drug is not ready for people. Scientists still have to test it on humans. This is going to take many years. But for the first time, scientists believe they can do more than just slow Alzheimer's. They think they can bring back what the disease takes away.
Alzheimer's Drug Helps Mice
Think Ahead: What do you think scientists need to learn next?
a) Whether mice can remember human faces.
b) Whether the drug may also help people.
c) Whether Alzheimer's can be spread between animals.
Ask: (1) Do you have a good memory? (2) Have you ever heard of Alzheimer's disease?
-
Disease (n.)
-
Drug (n.)
-
Memory (n.)
-
Treatment (n.)
-
Affect (v.)
-
Function (n.)
-
Energy (n.)
-
Dementia (n.)

Scientists say they brought back brain function in mice with Alzheimer's disease. Alzheimer's is a brain disease. It slowly takes away a person's memory and thinking. It mostly affects people over 65. It is the main cause of dementia (when the brain stops working well). More than 150 million people could have dementia by 2050.
The scientists tested a new drug on sick mice. The drug helped the mice's brains get energy again. Even very sick mice got better after the treatment. Their brains started working normally again.
The scientists tested the drug on two different groups of mice. In both groups, the drug stopped the disease or brought back brain function. The scientists now think that even very bad Alzheimer's can get better.
But the drug is not ready for people. Scientists still have to test it on humans. This is going to take many years. But for the first time, scientists believe they can do more than just slow Alzheimer's. They think they can bring back what the disease takes away.
Listen and Fill Gaps
Listen to the audio on eslnewsstories.com and complete the gaps below:
Scientists say they brought back brain function in mice with Alzheimer's disease. Alzheimer's is a brain disease. It slowly takes away a person's (1) and thinking. It mostly affects people over 65. It is the main (2) of dementia (when the brain stops working well). More than 150 million people could have dementia by 2050.
The scientists tested a new drug on sick mice. The drug helped the mice's brains get (3) again. Even very sick mice got better after the treatment. Their brains started working normally again.
The scientists tested the drug on two different (4) of mice. In both groups, the drug stopped the disease or brought back brain function. The scientists now think that even very bad Alzheimer's can get better.
But the drug is not ready for people. Scientists still have to test it on humans. This is going to take many years. But for the first time, scientists believe they can do more than just (5) Alzheimer's. They think they can bring back what the disease takes away.
True or False
Answer each question by selecting True or False, then click CHECK to see your results.
True or False
1. Alzheimer's disease mostly affects people over 65. TRUEFALSE True
2. The scientists tested the drug on humans. TRUEFALSE False
3. The drug is ready for people now. TRUEFALSE False
Put Events in Order
Put the events in the order they happened, from first to last.
- 1 Scientists tested a new drug on sick mice.
- 2 The drug helped the mice's brains get energy again.
- 3 Scientists will test the drug on humans.
- 4 In 2050, more than 150 million people could have dementia.
Put Events in Order
Put the events from the story in the correct order from first (1) to last (4):
- Scientists will test the drug on humans.
- Scientists tested a new drug on sick mice.
- In 2050, more than 150 million people could have dementia.
- The drug helped the mice's brains get energy again.
- Scientists tested a new drug on sick mice.
- The drug helped the mice's brains get energy again.
- Scientists will test the drug on humans.
- In 2050, more than 150 million people could have dementia.
Multiple Choice
Answer each question by selecting A, B, or C, then click CHECK to see your results.
Multiple Choice
1. What did the new drug help the mice's brains do?
a) Get energy againCorrect
b) Grow bigger
c) Make new cells
2. How many people could have dementia by 2050?
a) About 100 million
b) More than 150 millionCorrect
c) More than 200 million
3. What do the scientists now believe they can do?
a) Stop all brain diseases
b) Slow Alzheimer's only
c) Bring back what the disease takes awayCorrect
Listen and Fill Gaps
Listen to the audio and complete the gaps below:
Loading listening activity...
Vocab Match
Drag each vocabulary word to its matching definition, or select a word and then select its definition:
Loading vocabulary activity...
Vocab Match
Write each vocabulary word next to its matching definition.
1. Diseasee) A sickness that affects the body or mind.
2. Memoryd) The ability to remember things.
3. Treatmentc) Something done to make a sick person better.
4. Functionb) The way something works.
5. Dementiaa) When the brain stops working well.
a) When the brain stops working well.
b) The way something works.
c) Something done to make a sick person better.
d) The ability to remember things.
e) A sickness that affects the body or mind.
Discussion Builder
1) Opinion 2) Reason 3) Result
Discussion Builder
Choose the best phrase for each gap:
More than 150 million people could have dementia by 2050. that is a very big number.
I think, / But, / So,
More than 150 million people could have dementia by 2050. I think, that is a very big number.
Scientists need more time the drug is not ready for people.
because / and / but
Scientists need more time because the drug is not ready for people.
The drug worked on very sick mice. scientists are very happy about the results.
For example, / But, / So,
The drug worked on very sick mice. So, scientists are very happy about the results.
Discussion Questions
- How does this article make you feel? Why?
- What things do you remember well?
- What kinds of things do you often forget?
- Are you worried about getting old?
- Who is the oldest person you know? How are they different from you?
- What do you do to keep your brain healthy?
- Have you ever taken care of a sick person? What was it like?
- Why do you think scientists test drugs on mice first?
- What other diseases do you think need more research?
Discussion Questions
- How does this article make you feel? Why?
- What things do you remember well?
- What kinds of things do you often forget?
- Are you worried about getting old?
- Who is the oldest person you know? How are they different from you?
- What do you do to keep your brain healthy?
- Have you ever taken care of a sick person? What was it like?
- Why do you think scientists test drugs on mice first?
- What other diseases do you think need more research?
Answers
Listening: (1) memory, (2) cause, (3) energy, (4) groups, (5) slow
True or False:
- True. The article says it mostly affects people over 65.
- False. The article says the drug is not ready for people and scientists still have to test it on humans.
- False. The article says the drug is not ready for people and testing on humans is going to take many years.
Multiple Choice: a, b, c
Put Events in Order:
- Scientists tested a new drug on sick mice.
- The drug helped the mice's brains get energy again.
- Scientists will test the drug on humans.
- In 2050, more than 150 million people could have dementia.
Vocabulary:
- Disease: A sickness that affects the body or mind.
- Memory: The ability to remember things.
- Treatment: Something done to make a sick person better.
- Function: The way something works.
- Dementia: When the brain stops working well.
Discussion Builder:
Hints: 1) Opinion. 2) Reason. 3) Result.
- I think,
- because
- So,